Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
FMN2	FPERAYLLR	LUNG	915	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.11	RERFLCAD2	N	8	0	0	N
FMN2	QAYSLCPLY	LUNG	929	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.11	RERFLCAD2	N	10	0	0	N
FMN2	RRLYPEQAY	LUNG	923	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.11	RERFLCAD2	N	5	0	0	N
FMN2	TKDQLGLGH	LARGE_INTESTINE	172	p.G168fs	c.502_503delGG	Frame_Shift_Del	6	0.11	CL40	N	1	0	0	N
FMN2	TRSSPPATS	ENDOMETRIUM	411	p.P410fs	c.1228_1228delC	Frame_Shift_Del	6	0.11	AN3CA	N	2	0	0	N
FMN2	ALYQPHRCV	ENDOMETRIUM	1252	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	7	10	0	N
FMN2	ALYQPHRCV	LUNG	1252	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	7	10	0	N
FMN2	AYLLHPLYP	ENDOMETRIUM	1018	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	AYLLHPLYP	ENDOMETRIUM	1062	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	AYLLHPLYP	ENDOMETRIUM	1139	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	AYLLHPLYP	LUNG	1018	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	AYLLHPLYP	LUNG	1062	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	AYLLHPLYP	LUNG	1139	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	AYLLRPLYP	ENDOMETRIUM	1106	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	AYLLRPLYP	LUNG	1106	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	ERAYLLHPL	ENDOMETRIUM	1016	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	7	10	0	N
FMN2	ERAYLLHPL	ENDOMETRIUM	1060	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	7	10	0	N
FMN2	ERAYLLHPL	ENDOMETRIUM	1137	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	7	10	0	N
FMN2	ERAYLLHPL	LUNG	1016	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	7	10	0	N
FMN2	ERAYLLHPL	LUNG	1060	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	7	10	0	N
FMN2	ERAYLLHPL	LUNG	1137	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	7	10	0	N
FMN2	EWAYLLRPL	ENDOMETRIUM	1104	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	6	0	0	N
FMN2	EWAYLLRPL	LUNG	1104	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	6	0	0	N
FMN2	FPERAYLLH	ENDOMETRIUM	1014	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	0	N
FMN2	FPERAYLLH	ENDOMETRIUM	1058	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	0	N
FMN2	FPERAYLLH	ENDOMETRIUM	1135	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	0	N
FMN2	FPERAYLLH	LUNG	1014	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	0	N
FMN2	FPERAYLLH	LUNG	1058	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	0	N
FMN2	FPERAYLLH	LUNG	1135	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	0	N
FMN2	GQESHRPLC	ENDOMETRIUM	1229	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	1	0	0	N
FMN2	GQESHRPLC	LUNG	1229	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	1	0	0	N
FMN2	GVALYQPHR	ENDOMETRIUM	1250	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	6	0	0	N
FMN2	GVALYQPHR	LUNG	1250	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	6	0	0	N
FMN2	HLGQESHRP	ENDOMETRIUM	1227	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	HLGQESHRP	LUNG	1227	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	HPLYPEWAY	ENDOMETRIUM	1143	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	10	0	0	N
FMN2	HPLYPEWAY	LUNG	1143	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	10	0	0	N
FMN2	HSSHKLGVA	ENDOMETRIUM	1244	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	2	0	0	N
FMN2	HSSHKLGVA	LUNG	1244	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	2	0	0	N
FMN2	LFPERAYLL	ENDOMETRIUM	1013	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	11	11	2	N
FMN2	LFPERAYLL	ENDOMETRIUM	1057	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	11	11	2	N
FMN2	LFPERAYLL	ENDOMETRIUM	1134	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	11	11	2	N
FMN2	LFPERAYLL	LUNG	1013	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	11	11	2	N
FMN2	LFPERAYLL	LUNG	1057	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	11	11	2	N
FMN2	LFPERAYLL	LUNG	1134	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	11	11	2	N
FMN2	LFPERAYLL	LUNG	914	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	11	11	2	N
FMN2	LGVALYQPH	ENDOMETRIUM	1249	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	LGVALYQPH	LUNG	1249	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	LHLGQESHR	ENDOMETRIUM	1226	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	1	0	0	N
FMN2	LHLGQESHR	LUNG	1226	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	1	0	0	N
FMN2	LLHPLYPEW	ENDOMETRIUM	1141	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	4	0	0	N
FMN2	LLHPLYPEW	LUNG	1141	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	4	0	0	N
FMN2	LYPEWAYLL	ENDOMETRIUM	1101	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	12	10	2	N
FMN2	LYPEWAYLL	LUNG	1101	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	12	10	2	N
FMN2	LYQALHSSH	ENDOMETRIUM	1239	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	LYQALHSSH	LUNG	1239	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	LYQPHRCVD	ENDOMETRIUM	1253	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	0	0	0	N
FMN2	LYQPHRCVD	LUNG	1253	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	0	0	0	N
FMN2	QESHRPLCF	ENDOMETRIUM	1230	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	6	0	0	N
FMN2	QESHRPLCF	LUNG	1230	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	6	0	0	N
FMN2	QPHRCVDFF	ENDOMETRIUM	1255	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	13	9	0	N
FMN2	QPHRCVDFF	LUNG	1255	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	13	9	0	N
FMN2	RAYLLHPLY	ENDOMETRIUM	1017	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	11	0	0	N
FMN2	RAYLLHPLY	ENDOMETRIUM	1061	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	11	0	0	N
FMN2	RAYLLHPLY	ENDOMETRIUM	1138	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	11	0	0	N
FMN2	RAYLLHPLY	LUNG	1017	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	11	0	0	N
FMN2	RAYLLHPLY	LUNG	1061	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	11	0	0	N
FMN2	RAYLLHPLY	LUNG	1138	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	11	0	0	N
FMN2	RPLYLEWEY	ENDOMETRIUM	1176	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	13	0	0	N
FMN2	RPLYLEWEY	ENDOMETRIUM	1187	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	13	0	0	N
FMN2	RPLYLEWEY	LUNG	1176	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	13	0	0	N
FMN2	RPLYLEWEY	LUNG	1187	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	13	0	0	N
FMN2	SSHKLGVAL	ENDOMETRIUM	1245	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	11	10	0	N
FMN2	SSHKLGVAL	LUNG	1245	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	11	10	0	N
FMN2	VALYQPHRC	ENDOMETRIUM	1251	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	4	0	10	N
FMN2	VALYQPHRC	LUNG	1251	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	4	0	10	N
FMN2	WAYLLRPLY	ENDOMETRIUM	1105	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	12	0	6	N
FMN2	WAYLLRPLY	LUNG	1105	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	12	0	6	N
FMN2	YLLHPLYPE	ENDOMETRIUM	1019	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	6	N
FMN2	YLLHPLYPE	ENDOMETRIUM	1063	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	6	N
FMN2	YLLHPLYPE	ENDOMETRIUM	1140	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	6	N
FMN2	YLLHPLYPE	LUNG	1019	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YLLHPLYPE	LUNG	1063	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YLLHPLYPE	LUNG	1140	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YLLHPLYPE	LUNG	975	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YLLRPLYLV	ENDOMETRIUM	1195	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	Y	12	12	10	N
FMN2	YLLRPLYLV	LUNG	1195	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	Y	12	12	10	N
FMN2	YLLRPLYPE	ENDOMETRIUM	1107	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	3	0	6	N
FMN2	YLLRPLYPE	LUNG	1107	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YLLRPLYPE	LUNG	942	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	3	0	6	N
FMN2	YPEWAYLLR	ENDOMETRIUM	1102	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	8	0	0	Y
FMN2	YPEWAYLLR	LUNG	1102	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	8	0	0	Y
FMN2	YQALHSSHK	ENDOMETRIUM	1240	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	6	0	11	N
FMN2	YQALHSSHK	LUNG	1240	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	6	0	11	N
FMN2	YQPHRCVDF	ENDOMETRIUM	1254	p.P983fs	c.2947_2947delC	Frame_Shift_Del	6	0.22	HEC108	N	10	0	14	N
FMN2	YQPHRCVDF	LUNG	1254	p.P913fs	c.2737_2737delC	Frame_Shift_Del	6	0.22	RERFLCAD2	N	10	0	14	N