Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
MAP3K1AAPAGLRWRBREAST157p.R162fsc.485_485delGFrame_Shift_Del40.11MDAMB415N300N
MAP3K1AGLRWRIKKBREAST160p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415Y0110N
MAP3K1APAGLRWRIBREAST158p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415Y13140N
MAP3K1CTRWMIVQRBREAST173p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415Y5100N
MAP3K1GCTRWMIVQBREAST172p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415N000N
MAP3K1GLRWRIKKLBREAST161p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415Y11120N
MAP3K1IKKLSKGCTBREAST166p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N101N
MAP3K1KGCTRWMIVBREAST171p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415N700N
MAP3K1KKLSKGCTRBREAST167p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N100Y
MAP3K1KLSKGCTRWBREAST168p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415Y5110N
MAP3K1LRWRIKKLSBREAST162p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N2030N
MAP3K1LSKGCTRWMBREAST169p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415N301N
MAP3K1PAGLRWRIKBREAST159p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N000N
MAP3K1RIKKLSKGCBREAST165p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N100N
MAP3K1RWMIVQRNEBREAST175p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415N000N
MAP3K1RWRIKKLSKBREAST163p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N100N
MAP3K1SKGCTRWMIBREAST170p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415Y2130N
MAP3K1TRWMIVQRNBREAST174p.R162fsc.485_485delGFrame_Shift_Del60.11MDAMB415N200N
MAP3K1WRIKKLSKGBREAST164p.R162fsc.485_485delGFrame_Shift_Del50.11MDAMB415N3024N