Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MYST4 | ASRSIMSPA | LARGE_INTESTINE | 849 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 0 | N | ||||||||||||
| MYST4 | AVIWLDTSL | LARGE_INTESTINE | 836 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 11 | 0 | 0 | N | ||||||||||||
| MYST4 | DTSLRKSFA | LARGE_INTESTINE | 841 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | EPFLFMSLQ | LARGE_INTESTINE | 822 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 3 | 0.11 | SNUC2A | N | 2 | 0 | 0 | Y | ||||||||||||
| MYST4 | FASRSIMSP | LARGE_INTESTINE | 848 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 4 | N | ||||||||||||
| MYST4 | FLFMSLQKM | LARGE_INTESTINE | 824 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 4 | 0.11 | SNUC2A | N | 13 | 0 | 21 | N | ||||||||||||
| MYST4 | FMSLQKMMK | LARGE_INTESTINE | 826 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 7 | 0 | 26 | N | ||||||||||||
| MYST4 | GPPHQGRGA | PROSTATE | 644 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 5 | 0.11 | NCIH660 | N | 8 | 0 | 0 | Y | ||||||||||||
| MYST4 | IWLDTSLRK | LARGE_INTESTINE | 838 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 6 | 0.11 | SNUC2A | N | 0 | 0 | 10 | N | ||||||||||||
| MYST4 | KIYCQTFAC | LARGE_INTESTINE | 798 | p.Q802fs | c.2405_2405delA | Frame_Shift_Del | 4 | 0.11 | KM12 | N | 4 | 0 | 0 | N | ||||||||||||
| MYST4 | KMMKRAVIW | LARGE_INTESTINE | 831 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 4 | 0 | 0 | N | ||||||||||||
| MYST4 | KRAVIWLDT | LARGE_INTESTINE | 834 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 0 | N | ||||||||||||
| MYST4 | KSFASRSIM | LARGE_INTESTINE | 846 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 6 | 0.11 | SNUC2A | Y | 10 | 9 | 0 | N | ||||||||||||
| MYST4 | KVTLRWGPP | PROSTATE | 638 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 4 | 0.11 | NCIH660 | N | 1 | 0 | 0 | N | ||||||||||||
| MYST4 | KYKVTLRWG | PROSTATE | 636 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 3 | 0.11 | NCIH660 | N | 1 | 0 | 0 | N | ||||||||||||
| MYST4 | LDTSLRKSF | LARGE_INTESTINE | 840 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 6 | 0 | 0 | N | ||||||||||||
| MYST4 | LFMSLQKMM | LARGE_INTESTINE | 825 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 4 | 0 | 2 | N | ||||||||||||
| MYST4 | LKYKVTLRW | PROSTATE | 635 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 3 | 0.11 | NCIH660 | N | 5 | 0 | 21 | N | ||||||||||||
| MYST4 | LQKMMKRAV | LARGE_INTESTINE | 829 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 4 | 0.11 | SNUC2A | N | 4 | 0 | 22 | Y | ||||||||||||
| MYST4 | LRKSFASRS | LARGE_INTESTINE | 844 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 16 | N | ||||||||||||
| MYST4 | LRWGPPHQG | PROSTATE | 641 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 5 | 0.11 | NCIH660 | N | 2 | 0 | 4 | N | ||||||||||||
| MYST4 | MKRAVIWLD | LARGE_INTESTINE | 833 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 0 | 0 | 1 | N | ||||||||||||
| MYST4 | MMKRAVIWL | LARGE_INTESTINE | 832 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | Y | 13 | 9 | 9 | N | ||||||||||||
| MYST4 | MSLQKMMKR | LARGE_INTESTINE | 827 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | Y | 4 | 9 | 0 | N | ||||||||||||
| MYST4 | PFLFMSLQK | LARGE_INTESTINE | 823 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 3 | 0.11 | SNUC2A | N | 0 | 0 | 0 | Y | ||||||||||||
| MYST4 | QKMMKRAVI | LARGE_INTESTINE | 830 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 0 | N | ||||||||||||
| MYST4 | RAVIWLDTS | LARGE_INTESTINE | 835 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 0 | Y | ||||||||||||
| MYST4 | RKSFASRSI | LARGE_INTESTINE | 845 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 2 | 0 | 0 | N | ||||||||||||
| MYST4 | RWGPPHQGR | PROSTATE | 642 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 6 | 0.11 | NCIH660 | N | 1 | 0 | 0 | N | ||||||||||||
| MYST4 | SFASRSIMS | LARGE_INTESTINE | 847 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | SKIYCQTFA | LARGE_INTESTINE | 797 | p.Q802fs | c.2405_2405delA | Frame_Shift_Del | 3 | 0.11 | KM12 | N | 2 | 0 | 0 | N | ||||||||||||
| MYST4 | SLQKMMKRA | LARGE_INTESTINE | 828 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 3 | 0 | 0 | N | ||||||||||||
| MYST4 | SLRKSFASR | LARGE_INTESTINE | 843 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | Y | 5 | 10 | 0 | N | ||||||||||||
| MYST4 | TLRWGPPHQ | PROSTATE | 640 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 5 | 0.11 | NCIH660 | Y | 0 | 12 | 0 | N | ||||||||||||
| MYST4 | TSLRKSFAS | LARGE_INTESTINE | 842 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | VIWLDTSLR | LARGE_INTESTINE | 837 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 6 | 0.11 | SNUC2A | N | 7 | 0 | 8 | N | ||||||||||||
| MYST4 | VTLRWGPPH | PROSTATE | 639 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 5 | 0.11 | NCIH660 | N | 0 | 0 | 2 | N | ||||||||||||
| MYST4 | WGPPHQGRG | PROSTATE | 643 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 5 | 0.11 | NCIH660 | N | 3 | 0 | 0 | N | ||||||||||||
| MYST4 | WLDTSLRKS | LARGE_INTESTINE | 839 | p.L825fs | c.2474_2474delT | Frame_Shift_Del | 5 | 0.11 | SNUC2A | N | 3 | 0 | 0 | N | ||||||||||||
| MYST4 | YKVTLRWGP | PROSTATE | 637 | p.T640fs | c.1919_1919delC | Frame_Shift_Del | 4 | 0.11 | NCIH660 | N | 3 | 0 | 0 | N | ||||||||||||
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