Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NCOA3 | AETQYIDSR | ENDOMETRIUM | 328 | p.T330fs | c.989_989delC | Frame_Shift_Del | 5 | 0.11 | MFE319 | N | 1 | 0 | 0 | N | ||||||||||||
| NCOA3 | CSYLPVLLM | ENDOMETRIUM | 622 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 7 | 0 | 0 | N | ||||||||||||
| NCOA3 | ESKGHKNYC | ENDOMETRIUM | 614 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 3 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| NCOA3 | ETQYIDSRW | ENDOMETRIUM | 329 | p.T330fs | c.989_989delC | Frame_Shift_Del | 5 | 0.11 | MFE319 | N | 1 | 0 | 0 | N | ||||||||||||
| NCOA3 | FSSSSQCPA | PROSTATE | 518 | p.S521fs | c.1563_1564delCT | Frame_Shift_Del | 4 | 0.11 | LNCAPCLONEFGC | N | 5 | 0 | 0 | N | ||||||||||||
| NCOA3 | GHAETQYID | ENDOMETRIUM | 326 | p.T330fs | c.989_989delC | Frame_Shift_Del | 4 | 0.11 | MFE319 | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | GHKNYCSYL | ENDOMETRIUM | 617 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 3 | 11 | 0 | N | ||||||||||||
| NCOA3 | HAETQYIDS | ENDOMETRIUM | 327 | p.T330fs | c.989_989delC | Frame_Shift_Del | 5 | 0.11 | MFE319 | N | 2 | 0 | 0 | N | ||||||||||||
| NCOA3 | HKNYCSYLP | ENDOMETRIUM | 618 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | IDSRWLMEL | ENDOMETRIUM | 333 | p.T330fs | c.989_989delC | Frame_Shift_Del | 5 | 0.11 | MFE319 | Y | 6 | 9 | 0 | N | ||||||||||||
| NCOA3 | KGHKNYCSY | ENDOMETRIUM | 616 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 8 | 12 | 0 | N | ||||||||||||
| NCOA3 | KNYCSYLPV | ENDOMETRIUM | 619 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 13 | 0 | 0 | N | ||||||||||||
| NCOA3 | LLMTGVIPP | ENDOMETRIUM | 628 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 12 | N | ||||||||||||
| NCOA3 | LPVLLMTGV | ENDOMETRIUM | 625 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 13 | 0 | 0 | N | ||||||||||||
| NCOA3 | NGHAETQYI | ENDOMETRIUM | 325 | p.T330fs | c.989_989delC | Frame_Shift_Del | 3 | 0.11 | MFE319 | N | 6 | 0 | 0 | N | ||||||||||||
| NCOA3 | NYCSYLPVL | ENDOMETRIUM | 620 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 7 | 9 | 0 | Y | ||||||||||||
| NCOA3 | PVLLMTGVI | ENDOMETRIUM | 626 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | QYIDSRWLM | ENDOMETRIUM | 331 | p.T330fs | c.989_989delC | Frame_Shift_Del | 6 | 0.11 | MFE319 | Y | 3 | 10 | 0 | N | ||||||||||||
| NCOA3 | SFSSSSQCP | PROSTATE | 517 | p.S521fs | c.1563_1564delCT | Frame_Shift_Del | 3 | 0.11 | LNCAPCLONEFGC | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | SKGHKNYCS | ENDOMETRIUM | 615 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 4 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| NCOA3 | SSQCPASHQ | PROSTATE | 521 | p.S521fs | c.1563_1564delCT | Frame_Shift_Del | 4 | 0.11 | LNCAPCLONEFGC | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | SSSQCPASH | PROSTATE | 520 | p.S521fs | c.1563_1564delCT | Frame_Shift_Del | 5 | 0.11 | LNCAPCLONEFGC | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | SSSSQCPAS | PROSTATE | 519 | p.S521fs | c.1563_1564delCT | Frame_Shift_Del | 5 | 0.11 | LNCAPCLONEFGC | N | 0 | 0 | 0 | N | ||||||||||||
| NCOA3 | SYLPVLLMT | ENDOMETRIUM | 623 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 3 | 0 | 0 | N | ||||||||||||
| NCOA3 | TQYIDSRWL | ENDOMETRIUM | 330 | p.T330fs | c.989_989delC | Frame_Shift_Del | 6 | 0.11 | MFE319 | Y | 13 | 14 | 0 | N | ||||||||||||
| NCOA3 | VLLMTGVIP | ENDOMETRIUM | 627 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 2 | N | ||||||||||||
| NCOA3 | YCSYLPVLL | ENDOMETRIUM | 621 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 10 | 0 | 2 | Y | ||||||||||||
| NCOA3 | YIDSRWLME | ENDOMETRIUM | 332 | p.T330fs | c.989_989delC | Frame_Shift_Del | 6 | 0.11 | MFE319 | N | 2 | 0 | 0 | N | ||||||||||||
| NCOA3 | YLPVLLMTG | ENDOMETRIUM | 624 | p.K619fs | c.1855_1855delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 2 | 0 | 8 | N | ||||||||||||
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