Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
PDGFRAASKIVSTVILARGE_INTESTINE810p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115Y6160N
PDGFRAATSSWHKEKLARGE_INTESTINE822p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N300N
PDGFRACSLCTSRNDHAEMATOPOIETIC_AND_LYMPHOID_TISSUE125p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N100N
PDGFRACTSRNDGLFHAEMATOPOIETIC_AND_LYMPHOID_TISSUE128p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1N200N
PDGFRADGLFSHRGGHAEMATOPOIETIC_AND_LYMPHOID_TISSUE133p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1N000N
PDGFRADPCSLCTSRHAEMATOPOIETIC_AND_LYMPHOID_TISSUE123p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N300N
PDGFRAEFLASKIVSLARGE_INTESTINE807p.S811fsc.2433_2433delAFrame_Shift_Del30.11HT115N000N
PDGFRAFLASKIVSTLARGE_INTESTINE808p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115N601N
PDGFRAIVSTVIWLLLARGE_INTESTINE813p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115Y1194N
PDGFRAIWLLATSSWLARGE_INTESTINE818p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N205N
PDGFRAIYVPDPCSLHAEMATOPOIETIC_AND_LYMPHOID_TISSUE119p.T124fsc.372_373delAGFrame_Shift_Del30.11KASUMI1Y890N
PDGFRAKIVSTVIWLLARGE_INTESTINE812p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115Y1890N
PDGFRALASKIVSTVLARGE_INTESTINE809p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N802N
PDGFRALATSSWHKELARGE_INTESTINE821p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N000N
PDGFRALCTSRNDGLHAEMATOPOIETIC_AND_LYMPHOID_TISSUE127p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N800Y
PDGFRALLATSSWHKLARGE_INTESTINE820p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N603N
PDGFRAMEFLASKIVLARGE_INTESTINE806p.S811fsc.2433_2433delAFrame_Shift_Del20.11HT115N1202N
PDGFRANDGLFSHRGHAEMATOPOIETIC_AND_LYMPHOID_TISSUE132p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1N000N
PDGFRAPCSLCTSRNHAEMATOPOIETIC_AND_LYMPHOID_TISSUE124p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N
PDGFRAPDPCSLCTSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE122p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N
PDGFRARNDGLFSHRHAEMATOPOIETIC_AND_LYMPHOID_TISSUE131p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1Y4110N
PDGFRASKIVSTVIWLARGE_INTESTINE811p.S811fsc.2433_2433delAFrame_Shift_Del30.11HT115N100N
PDGFRASLCTSRNDGHAEMATOPOIETIC_AND_LYMPHOID_TISSUE126p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N
PDGFRASRNDGLFSHHAEMATOPOIETIC_AND_LYMPHOID_TISSUE130p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1Y290N
PDGFRASTVIWLLATLARGE_INTESTINE815p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N100N
PDGFRATSRNDGLFSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE129p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1N100N
PDGFRATSSWHKEKLLARGE_INTESTINE823p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115Y7100N
PDGFRATVIWLLATSLARGE_INTESTINE816p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115N000N
PDGFRAVIWLLATSSLARGE_INTESTINE817p.S811fsc.2433_2433delAFrame_Shift_Del40.11HT115N009N
PDGFRAVPDPCSLCTHAEMATOPOIETIC_AND_LYMPHOID_TISSUE121p.T124fsc.372_373delAGFrame_Shift_Del50.11KASUMI1N600N
PDGFRAVSTVIWLLALARGE_INTESTINE814p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N300N
PDGFRAWLLATSSWHLARGE_INTESTINE819p.S811fsc.2433_2433delAFrame_Shift_Del50.11HT115N4014N
PDGFRAYIYVPDPCSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE118p.T124fsc.372_373delAGFrame_Shift_Del20.11KASUMI1N200N
PDGFRAYVPDPCSLCHAEMATOPOIETIC_AND_LYMPHOID_TISSUE120p.T124fsc.372_373delAGFrame_Shift_Del40.11KASUMI1N5013N