Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
PDGFRACSLCTSRNDHAEMATOPOIETIC_AND_LYMPHOID_TISSUE125p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N100N
PDGFRADPCSLCTSRHAEMATOPOIETIC_AND_LYMPHOID_TISSUE123p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N300N
PDGFRALCTSRNDGLHAEMATOPOIETIC_AND_LYMPHOID_TISSUE127p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N800Y
PDGFRAPCSLCTSRNHAEMATOPOIETIC_AND_LYMPHOID_TISSUE124p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N
PDGFRAPDPCSLCTSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE122p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N
PDGFRASLCTSRNDGHAEMATOPOIETIC_AND_LYMPHOID_TISSUE126p.T124fsc.372_373delAGFrame_Shift_Del60.11KASUMI1N000N