Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3C2G | ALRPVHMLN | OVARY | 1357 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | DWCRWYLML | OVARY | 965 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | N | 8 | 0 | 0 | N | ||||||||||||
| PIK3C2G | EKTKDWCRW | OVARY | 961 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | FIFYHIPVK | OVARY | 1366 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 7 | 0 | 11 | N | ||||||||||||
| PIK3C2G | FILCHVLII | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 298 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 14 | 10 | 49 | N | ||||||||||||
| PIK3C2G | FVGGKQNLF | OVARY | 1375 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 6 | 0 | 1 | Y | ||||||||||||
| PIK3C2G | FYHIPVKFV | OVARY | 1368 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 7 | 11 | 12 | N | ||||||||||||
| PIK3C2G | GRSGALLQH | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 266 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 2 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HFRISSFLR | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 274 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 2 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HIPVKFVGG | OVARY | 1370 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HMLNFIFYH | OVARY | 1362 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 3 | 9 | 0 | N | ||||||||||||
| PIK3C2G | HNLFILCHV | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 295 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 3 | 16 | 0 | N | ||||||||||||
| PIK3C2G | IFYHIPVKF | OVARY | 1367 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 9 | 10 | 15 | N | ||||||||||||
| PIK3C2G | ISQMALRPV | OVARY | 1353 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 4 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ITQHNLFIL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 292 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 13 | 11 | 1 | N | ||||||||||||
| PIK3C2G | KDWCRWYLM | OVARY | 964 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | Y | 8 | 10 | 0 | N | ||||||||||||
| PIK3C2G | KTKDWCRWY | OVARY | 962 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | Y | 6 | 14 | 0 | N | ||||||||||||
| PIK3C2G | LNFIFYHIP | OVARY | 1364 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | LQHFRISSF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 272 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 10 | 0 | 8 | N | ||||||||||||
| PIK3C2G | MALRPVHML | OVARY | 1356 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 22 | 9 | 11 | N | ||||||||||||
| PIK3C2G | MLNFIFYHI | OVARY | 1363 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 11 | 13 | 5 | N | ||||||||||||
| PIK3C2G | NFIFYHIPV | OVARY | 1365 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 3 | 0 | 0 | N | ||||||||||||
| PIK3C2G | NISQMALRP | OVARY | 1352 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | QHNLFILCH | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 294 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | QMALRPVHM | OVARY | 1355 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 3 | 11 | 0 | N | ||||||||||||
| PIK3C2G | SQMALRPVH | OVARY | 1354 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | TKDWCRWYL | OVARY | 963 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | Y | 4 | 11 | 0 | N | ||||||||||||
| PIK3C2G | YHIPVKFVG | OVARY | 1369 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 2 | 0 | 7 | N | ||||||||||||
| PIK3C2G | DNWGKSQVC | LARGE_INTESTINE | 840 | p.E841fs | c.2521_2522insA | Frame_Shift_Ins | 6 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | GDNWGKSQV | LARGE_INTESTINE | 839 | p.E841fs | c.2521_2522insA | Frame_Shift_Ins | 6 | 0.11 | CW2 | N | 3 | 0 | 0 | N | ||||||||||||
| PIK3C2G | NWGKSQVCQ | LARGE_INTESTINE | 841 | p.E841fs | c.2521_2522insA | Frame_Shift_Ins | 6 | 0.11 | CW2 | N | 0 | 0 | 0 | Y | ||||||||||||
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