Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FMN2 | LPPPPPPPP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 908 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | EB2 | N | 1 | 0 | 0 | Y | ||||||||||||
| FMN2 | LPPPPPPPP | BONE | 908 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | SJSA1 | N | 1 | 0 | 0 | Y | ||||||||||||
| FMN2 | MLPPPPPPP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 907 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | EB2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | MLPPPPPPP | BONE | 907 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | SJSA1 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | PPPPPPPLP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 910 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | EB2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | PPPPPPPLP | BONE | 910 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 1 | 0.22 | SJSA1 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | PPPPPPPPL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 909 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 2 | 0.22 | EB2 | N | 10 | 0 | 0 | Y | ||||||||||||
| FMN2 | PPPPPPPPL | BONE | 909 | p.917_918insPP | c.2739_2740insCCCCCT | In_Frame_Ins | 2 | 0.22 | SJSA1 | N | 10 | 0 | 0 | Y | ||||||||||||
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