Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MSH2 | ALIQIGPKE | OVARY | 189 | p.L191del | c.568_570delCTC | In_Frame_Del | 1 | 0.11 | OC316 | N | 0 | 0 | 0 | N | ||||||||||||
| MSH2 | AQLDAVSFA | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 600 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 3 | 0.11 | HT | N | 6 | 0 | 0 | N | ||||||||||||
| MSH2 | AVSFAHVSN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 604 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 1 | 0.11 | HT | N | 0 | 0 | 0 | N | ||||||||||||
| MSH2 | DAVSFAHVS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 603 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 2 | 0.11 | HT | N | 1 | 0 | 0 | N | ||||||||||||
| MSH2 | DLLVRQYRV | LUNG | 91 | p.L94del | c.273_275delTCT | In_Frame_Del | 1 | 0.11 | NCIH1734 | Y | 8 | 9 | 0 | N | ||||||||||||
| MSH2 | EALIQIGPK | OVARY | 188 | p.L191del | c.568_570delCTC | In_Frame_Del | 2 | 0.11 | OC316 | N | 1 | 0 | 0 | N | ||||||||||||
| MSH2 | ESFVKDLLV | LUNG | 86 | p.L94del | c.273_275delTCT | In_Frame_Del | 1 | 0.11 | NCIH1734 | N | 9 | 0 | 0 | N | ||||||||||||
| MSH2 | FSNLEALIQ | OVARY | 184 | p.L191del | c.568_570delCTC | In_Frame_Del | 2 | 0.11 | OC316 | N | 2 | 0 | 17 | N | ||||||||||||
| MSH2 | FVKDLLVRQ | LUNG | 88 | p.L94del | c.273_275delTCT | In_Frame_Del | 3 | 0.11 | NCIH1734 | N | 2 | 0 | 12 | N | ||||||||||||
| MSH2 | KDLLVRQYR | LUNG | 90 | p.L94del | c.273_275delTCT | In_Frame_Del | 2 | 0.11 | NCIH1734 | N | 0 | 0 | 0 | N | ||||||||||||
| MSH2 | LAQLDAVSF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 599 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 2 | 0.11 | HT | N | 7 | 0 | 2 | N | ||||||||||||
| MSH2 | LDAVSFAHV | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 602 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 3 | 0.11 | HT | N | 4 | 0 | 0 | N | ||||||||||||
| MSH2 | LEALIQIGP | OVARY | 187 | p.L191del | c.568_570delCTC | In_Frame_Del | 3 | 0.11 | OC316 | N | 0 | 0 | 0 | N | ||||||||||||
| MSH2 | NLEALIQIG | OVARY | 186 | p.L191del | c.568_570delCTC | In_Frame_Del | 4 | 0.11 | OC316 | N | 1 | 0 | 0 | N | ||||||||||||
| MSH2 | QFSNLEALI | OVARY | 183 | p.L191del | c.568_570delCTC | In_Frame_Del | 1 | 0.11 | OC316 | N | 4 | 0 | 0 | N | ||||||||||||
| MSH2 | QLDAVSFAH | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 601 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 4 | 0.11 | HT | N | 2 | 0 | 0 | N | ||||||||||||
| MSH2 | SFVKDLLVR | LUNG | 87 | p.L94del | c.273_275delTCT | In_Frame_Del | 2 | 0.11 | NCIH1734 | N | 2 | 0 | 0 | N | ||||||||||||
| MSH2 | SNLEALIQI | OVARY | 185 | p.L191del | c.568_570delCTC | In_Frame_Del | 3 | 0.11 | OC316 | Y | 7 | 10 | 0 | N | ||||||||||||
| MSH2 | VKDLLVRQY | LUNG | 89 | p.L94del | c.273_275delTCT | In_Frame_Del | 3 | 0.11 | NCIH1734 | N | 5 | 0 | 4 | N | ||||||||||||
| MSH2 | VLAQLDAVS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 598 | p.V606del | c.1816_1818delGTC | In_Frame_Del | 1 | 0.11 | HT | N | 0 | 0 | 0 | N | ||||||||||||
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