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This page gives details of CPPsite entry with ID 2253
Primary information
CPPsite ID2253
PEPTIDE SEQUENCECyclo (FΦRRRRQ)
PEPTIDE NAMEbicyclo(FΦR4-RARAR)Rho
CHIRALITYModified
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONΦ, L-2-naphthylalanine, J, l-2,3-diaminopropionic acid, Tm, trimesoyl
UPTAKE EFFICIENCYHigher efficiency
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHEK293, HeLa, MCF-7, NIH 3T3, A549, Jurkat, H1650, and H1299 cells
CARGOCyclic peptide Tm(RARAR)K
PMID24896852
PATENTUnknown
LENGTH8
Secondary StructureNA
SMILESNA
3-D StructureNot Predicted