dbEM

Protein: KAT6A

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KAT6A!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
3.7e-50
PF00628 PHD 265 312 2.6e-10
PF01853 MOZ_SAS 562 746 2e-89
PB006470 Pfam-B_6470 1487 1600 1.5e-45

2. Superfamily Domains:

Domain ID Start Site End Site E-value
0053259 508 776 6.07e-112
0050474 251 322 1.20e-17
0051371 92 175 4.63e-07
0050474 195 263 2.66e-05
Sequence Alignment (+)

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1. Sequence alignment with 1000 genome variations:

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:
  Sequence Profiles (+)

HMM
  With Uniprot database     With Mutants      With 1000 Genome Variants
PSSM
  With Uniprot database     With Mutants      With 1000 Genome Variant

Post Translational Modifications (+)

S. No.	Position	Amino acid	Type
1	1007	K	Acetylation
2	1007	K	Acetylation
3	1089	S	Phosphorylation
4	1104	S	Phosphorylation
5	1113	S	Phosphorylation
6	1113	S	Phosphorylation
7	28	S	Phosphorylation
8	350	K	Acetylation
9	350	K	Acetylation
10	355	K	Acetylation
11	355	K	Acetylation
12	415	K	Acetylation
13	418	T	Phosphorylation
14	418	T	Phosphorylation
15	420	S	Phosphorylation
16	420	S	Phosphorylation
17	447	S	Phosphorylation
18	449	T	Phosphorylation
19	449	T	Phosphorylation
20	473	S	Phosphorylation
21	473	S	Phosphorylation
22	604	K	Acetylation
23	604	K	Acetylation
24	815	K	Acetylation
25	815	K	Acetylation
26	842	S	Phosphorylation
27	909	T	Phosphorylation
28	909	T	Phosphorylation
29	941	S	Phosphorylation
30	941	S	Phosphorylation

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
KAT6A	KAT6A	KAT6A	ENSP00000265713	Q92794
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
Q92794	KAT6A	ENSP00000265713	KAT6A	Q92794
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
KAT6A	ENSP00000265713	601408	Q92794	PA37592

Domain ID	Domain Name	Start Site	End Site	E-value
		3.7e-50
PF00628	PHD	265	312	2.6e-10
PF01853	MOZ_SAS	562	746	2e-89
PB006470	Pfam-B_6470	1487	1600	1.5e-45

Modelled Structure	Structures available in PDB

Domain ID	Start Site	End Site	E-value
0053259	508	776	6.07e-112
0050474	251	322	1.20e-17
0051371	92	175	4.63e-07
0050474	195	263	2.66e-05

dbEM

Protein: KAT6A

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)