dbEM

Protein: KAT8

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KAT8!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

2GIV, 2PQ8, 2Y0M, 3QAH, 3TOA, 3TOB, 4DNC,
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
PF11717 Tudor-knot 55 110 3e-21
PF01853 MOZ_SAS 232 417 6e-93

2. Superfamily Domains:

Domain ID Start Site End Site E-value
0053259 177 445 1.94e-112
0050533 49 175 3.16e-40

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1. Sequence alignment with 1000 genome variations:

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2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:

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Modelled Structure	Structures available in PDB
	2GIV, 2PQ8, 2Y0M, 3QAH, 3TOA, 3TOB, 4DNC,