dbEM

Protein: KDM7A

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Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KDM7A!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78,
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
PB003779 Pfam-B_3779 37 66 7.8e-08
PF00628 PHD 39 86 1e-08
PF02373 JmjC 269 369 3.2e-10
PB018122 Pfam-B_18122 381 539 9e-104
PB013686 Pfam-B_13686 541 639 2.2e-45

2. Superfaimly domains are not present!!
Sequence Alignment (+)

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1. Sequence alignment with 1000 genome variations:

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:
  Sequence Profiles (+)

HMM
  With Uniprot database     With Mutants      With 1000 Genome Variants
PSSM
  With Uniprot database     With Mutants      With 1000 Genome Variant
Post Translational Modifications (+)

Post translational modifications are not found!!
Other Databases Link (+)

Proteomics DB COSMIC Gene Atlas STRING PIR

KDM7A KDM7A KDM7A

QuickGO HGNC Ensembl Genome Browser TreeFam UniProt

KDM7A KDM7A

Expression Atlas Protein Atlas OMIM IntAct PharmGKB

KDM7A

CSIR-IMTECH

Raghava's Group

Modelled Structure	Structures available in PDB
	3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78,

Domain ID	Domain Name	Start Site	End Site	E-value
PB003779	Pfam-B_3779	37	66	7.8e-08
PF00628	PHD	39	86	1e-08
PF02373	JmjC	269	369	3.2e-10
PB018122	Pfam-B_18122	381	539	9e-104
PB013686	Pfam-B_13686	541	639	2.2e-45

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
KDM7A	KDM7A	KDM7A
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
	KDM7A		KDM7A
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
KDM7A

dbEM

Protein: KDM7A

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)