dbEM

Protein: KDM8

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KDM8!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

3UYJ, 4AAP, 4GAZ, 4GJY, 4GJZ,
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
PF13621 Cupin_8 194 415 2.5e-49

2. Superfamily Domains:

Domain ID Start Site End Site E-value
0050303 183 415 2.20e-69

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1. Sequence alignment with 1000 genome variations:

Click on button to get Sequence alignment with Coverage, Consensus and Quality

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:

Click on button to get Sequence alignment with Coverage, Consensus and Quality

  Sequence Profiles (+)

HMM
  With Uniprot database     With Mutants      With 1000 Genome Variants
PSSM
  With Uniprot database     With Mutants      With 1000 Genome Variant
Post Translational Modifications (+)

Post translational modifications are not found!!

Modelled Structure	Structures available in PDB
	3UYJ, 4AAP, 4GAZ, 4GJY, 4GJZ,

Domain ID	Domain Name	Start Site	End Site	E-value
PF13621	Cupin_8	194	415	2.5e-49