dbEM

Protein: KMT2B

Expand All | Collapse All

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KMT2B!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

Users must enabled the Java in their browser to see structure.
Users can also download Java from here.

Modelled Structure Structures available in PDB
Structure Domains (+)

1. PFAM domains are not present!!

2. Superfaimly domains are not present!!
Sequence Alignment (+)

Users must enabled the Java in their browser to see sequence alignments.
Users can also download Java from here.

1. Variants are not present in 1000 Genomes!!

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:
  Sequence Profiles (+)

HMM
  With Uniprot database     With Mutants      With 1000 Genome Variants
PSSM
  With Uniprot database     With Mutants      With 1000 Genome Variant
Post Translational Modifications (+)

Post translational modifications are not found!!
Other Databases Link (+)

Proteomics DB COSMIC Gene Atlas STRING PIR

KMT2B KMT2B KMT2B

QuickGO HGNC Ensembl Genome Browser TreeFam UniProt

KMT2B KMT2B

Expression Atlas Protein Atlas OMIM IntAct PharmGKB

KMT2B

CSIR-IMTECH

Raghava's Group

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
KMT2B	KMT2B	KMT2B
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
	KMT2B		KMT2B
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
KMT2B

Modelled Structure	Structures available in PDB

dbEM

Protein: KMT2B

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)