dbEM

Protein: KMT2E

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KMT2E!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

1. PFAM Domains:

2. Superfamily Domains:

Sequence Alignment (+)

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1. Sequence alignment with 1000 genome variations:

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:
  Sequence Profiles (+)

HMM
  With Uniprot database     With Mutants      With 1000 Genome Variants
PSSM
  With Uniprot database     With Mutants      With 1000 Genome Variant
Post Translational Modifications (+)

Post translational modifications are not found!!
Other Databases Link (+)

Proteomics DB COSMIC Gene Atlas STRING PIR

KMT2E KMT2E KMT2E

QuickGO HGNC Ensembl Genome Browser TreeFam UniProt

KMT2E KMT2E

Expression Atlas Protein Atlas OMIM IntAct PharmGKB

KMT2E

Modelled Structure	Structures available in PDB