dbEM

#	Cell Line/Tumor sample	Tissue of Origin	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	587238	LARGE INTESTINE	c.2540G>A	p.R847H	COSMIC	PASSENGER/OTHER	Benign
2	587284	LARGE INTESTINE	c.2428C>T	p.R810W	COSMIC	PASSENGER/OTHER	Benign
3	587338	LARGE INTESTINE	c.1306G>A	p.A436T	COSMIC	PASSENGER/OTHER	Benign
4	587376	LARGE INTESTINE	c.1529T>C	p.V510A	COSMIC	PASSENGER/OTHER	Probably Damaging
5	ESO-0053	OESOPHAGUS	c.2588A>T	p.Q863L	COSMIC	PASSENGER/OTHER	Probably Damaging
6	ESO-0129	OESOPHAGUS	c.3073A>G	p.K1025E	COSMIC	PASSENGER/OTHER	Benign
7	HCC34T	LIVER	c.907G>T	p.A303S	COSMIC	PASSENGER/OTHER	Benign
8	HN_63039	UPPER AERODIGESTIVE TRACT	c.1354G>A	p.A452T	COSMIC	PASSENGER/OTHER	Benign
9	LC_C15	LUNG	c.2026G>A	p.E676K	COSMIC	PASSENGER/OTHER	Benign
10	LUAD-LIP77	LUNG	c.1253G>T	p.G418V	COSMIC	PASSENGER/OTHER	Probably Damaging
11	LUAD-NYU1021	LUNG	c.2254C>T	p.L752F	COSMIC	PASSENGER/OTHER	Possibly Damaging
12	LUAD-RT-S01700	LUNG	c.2253G>T	p.T751T	COSMIC	NP	NP
13	LUAD-RT-S01813	LUNG	c.2392A>T	p.R798W	COSMIC	PASSENGER/OTHER	Possibly Damaging
14	LUAD-YINHD	LUNG	c.336G>A	p.K112K	COSMIC	NP	NP
15	LUAD-YINHD	LUNG	c.999G>C	p.L333L	COSMIC	NP	NP
16	Patient4_Tu	HAEMATOPOIETIC AND LYMPHOID TISSUE	c.2544C>G	p.I848M	COSMIC	PASSENGER/OTHER	Benign
17	RK086_C01	LIVER	c.1760G>A	p.R587H	COSMIC	PASSENGER/OTHER	Probably Damaging
18	SNB19	CENTRAL NERVOUS SYSTEM	c.1744G>A	p.E582K	COSMIC	PASSENGER/OTHER	Probably Damaging
19	SWE-2A	PROSTATE	c.2797C>T	p.L933F	COSMIC	PASSENGER/OTHER	Possibly Damaging
20	TCGA-05-5429-01	LUNG	c.1539T>C	p.D513D	COSMIC	NP	NP
21	TCGA-18-3409-01	LUNG	c.1271C>T	p.S424F	COSMIC	PASSENGER/OTHER	Probably Damaging
22	TCGA-22-5472-01	LUNG	c.1039C>A	p.L347I	COSMIC	PASSENGER/OTHER	Benign
23	TCGA-23-1026-01	OVARY	c.2036G>A	p.S679N	COSMIC	PASSENGER/OTHER	Benign
24	TCGA-44-2657-01	LUNG	c.2266G>T	p.D756Y	COSMIC	PASSENGER/OTHER	Benign
25	TCGA-44-2659-01	LUNG	c.709G>T	p.E237*	COSMIC	NP	NP
26	TCGA-49-4514-01	LUNG	c.2982G>A	p.R994R	COSMIC	NP	NP
27	TCGA-55-7907-01	LUNG	c.54A>G	p.V18V	COSMIC	NP	NP
28	TCGA-66-2795-01	LUNG	c.2179G>T	p.G727*	COSMIC	NP	NP
29	TCGA-78-7146-01	LUNG	c.828G>A	p.L276L	COSMIC	NP	NP
30	TCGA-78-7150-01	LUNG	c.682C>G	p.L228V	COSMIC	PASSENGER/OTHER	Benign
31	TCGA-78-7161-01	LUNG	c.633C>T	p.S211S	COSMIC	NP	NP
32	TCGA-A5-A0GP-01	ENDOMETRIUM	c.605A>G	p.D202G	COSMIC	PASSENGER/OTHER	Probably Damaging
33	TCGA-A5-A0VP-01	ENDOMETRIUM	c.2052C>T	p.V684V	COSMIC	NP	NP
34	TCGA-AA-3984-01	LARGE INTESTINE	c.68G>T	p.R23I	COSMIC	PASSENGER/OTHER	Probably Damaging
35	TCGA-AA-3994-01	LARGE INTESTINE	c.2032G>T	p.V678F	COSMIC	PASSENGER/OTHER	Benign
36	TCGA-AA-A00Z-01	LARGE INTESTINE	c.2709G>A	p.V903V	COSMIC	NP	NP
37	TCGA-AA-A022-01	LARGE INTESTINE	c.1599C>T	p.Y533Y	COSMIC	NP	NP
38	TCGA-AF-2691-01	LARGE INTESTINE	c.753G>T	p.L251F	COSMIC	PASSENGER/OTHER	Possibly Damaging
39	TCGA-AG-A002-01	LARGE INTESTINE	c.1349C>T	p.T450M	COSMIC	PASSENGER/OTHER	Benign
40	TCGA-AG-A002-01	LARGE INTESTINE	c.210G>T	p.K70N	COSMIC	PASSENGER/OTHER	Probably Damaging
41	TCGA-AP-A051-01	ENDOMETRIUM	c.61C>T	p.R21W	COSMIC	PASSENGER/OTHER	Probably Damaging
42	TCGA-AP-A056-01	ENDOMETRIUM	c.1084C>T	p.R362*	COSMIC	NP	NP
43	TCGA-AP-A056-01	ENDOMETRIUM	c.1710T>C	p.L570L	COSMIC	NP	NP
44	TCGA-AP-A059-01	ENDOMETRIUM	c.3032G>T	p.R1011I	COSMIC	PASSENGER/OTHER	Benign
45	TCGA-AP-A0LG-01	ENDOMETRIUM	c.2233T>G	p.S745A	COSMIC	PASSENGER/OTHER	Possibly Damaging
46	TCGA-AP-A0LM-01	ENDOMETRIUM	c.2054T>C	p.I685T	COSMIC	PASSENGER/OTHER	Possibly Damaging
47	TCGA-AP-A0LM-01	ENDOMETRIUM	c.2224G>A	p.G742R	COSMIC	PASSENGER/OTHER	Probably Damaging
48	TCGA-AP-A0LM-01	ENDOMETRIUM	c.908C>T	p.A303V	COSMIC	PASSENGER/OTHER	Possibly Damaging
49	TCGA-AQ-A04H-01	BREAST	c.2321G>T	p.R774L	COSMIC	PASSENGER/OTHER	Probably Damaging
50	TCGA-AX-A0J0-01	ENDOMETRIUM	c.2110G>A	p.E704K	COSMIC	PASSENGER/OTHER	Probably Damaging
51	TCGA-AX-A0J0-01	ENDOMETRIUM	c.3068G>A	p.R1023Q	COSMIC	PASSENGER/OTHER	Benign
52	TCGA-B5-A0JY-01	ENDOMETRIUM	c.1684C>T	p.P562S	COSMIC	PASSENGER/OTHER	Possibly Damaging
53	TCGA-B5-A11N-01	ENDOMETRIUM	c.2942C>T	p.P981L	COSMIC	PASSENGER/OTHER	Benign
54	TCGA-B5-A11Y-01	ENDOMETRIUM	c.308G>A	p.R103H	COSMIC	PASSENGER/OTHER	Possibly Damaging
55	TCGA-BH-A0HA-01	BREAST	c.2888A>G	p.Y963C	COSMIC	PASSENGER/OTHER	Probably Damaging
56	TCGA-BS-A0UV-01	ENDOMETRIUM	c.94C>T	p.R32*	COSMIC	NP	NP
57	TCGA-CA-6717-01	LARGE INTESTINE	c.3042G>T	p.K1014N	COSMIC	PASSENGER/OTHER	Benign
58	TCGA-CM-5861-01	LARGE INTESTINE	c.2530G>A	p.A844T	COSMIC	PASSENGER/OTHER	Benign
59	TCGA-D1-A0ZO-01	ENDOMETRIUM	c.637G>A	p.V213I	COSMIC	PASSENGER/OTHER	Benign
60	TCGA-D1-A103-01	ENDOMETRIUM	c.2738C>A	p.A913D	COSMIC	PASSENGER/OTHER	Benign
61	TCGA-D1-A167-01	ENDOMETRIUM	c.454C>T	p.R152W	COSMIC	PASSENGER/OTHER	Probably Damaging
62	TCGA-D1-A17H-01	ENDOMETRIUM	c.188T>C	p.L63P	COSMIC	PASSENGER/OTHER	Probably Damaging
63	TCGA-D1-A17Q-01	ENDOMETRIUM	c.822G>T	p.K274N	COSMIC	PASSENGER/OTHER	Benign
64	TCGA-D1-A17U-01	ENDOMETRIUM	c.25C>T	p.R9*	COSMIC	NP	NP
65	TCGA-DK-A1AC-01	URINARY TRACT	c.3032G>C	p.R1011T	COSMIC	PASSENGER/OTHER	Benign
66	TCGA-DK-A1AF-01	URINARY TRACT	c.612C>G	p.L204L	COSMIC	NP	NP
67	TCGA-E9-A1RB-01	BREAST	c.2340C>T	p.S780S	COSMIC	NP	NP
68	TCGA-FD-A3N6-01	URINARY TRACT	c.154C>T	p.R52W	COSMIC	PASSENGER/OTHER	Probably Damaging
69	TCGA-J2-8192-01	LUNG	c.2551C>G	p.L851V	COSMIC	PASSENGER/OTHER	Possibly Damaging
70	U251	CENTRAL NERVOUS SYSTEM	c.1744G>A	p.E582K	COSMIC	PASSENGER/OTHER	Probably Damaging
71	YUAVEY	SKIN	c.94C>T	p.R32*	COSMIC	NP	NP
72	YUFAR	SKIN	c.2077C>T	p.P693S	COSMIC	PASSENGER/OTHER	Possibly Damaging
73	YUNACK	SKIN	c.2077C>T	p.P693S	COSMIC	PASSENGER/OTHER	Possibly Damaging
74	YUZINO	SKIN	c.2863C>A	p.L955M	COSMIC	PASSENGER/OTHER	Benign

*NP: Not Predicted

Proteomics DB	COSMIC	Gene Atlas	STRING	PIR
NAT10	NAT10	NAT10
QuickGO	HGNC	Ensembl Genome Browser	TreeFam	UniProt
	NAT10		NAT10
Expression Atlas	Protein Atlas	OMIM	IntAct	PharmGKB
NAT10

dbEM

Protein: NAT10

Mutation Data (+)

Copy number variation and expression profile (+)

Gene Essentiality Data (+)

Tertiary structure (+)

Structure Domains (+)

Sequence Alignment (+)

Sequence Profiles (+)

Post Translational Modifications (+)

Other Databases Link (+)

Modelled Structure	Structures available in PDB