Epidermal Growth Factor Receptor Inhibitor Database
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| Activity against kinases | ||||||||||||||
| Molecule Id: EGIN0000208 | ||||||||||||||
| S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
| 1 | Jak3 | - | 3140 nM | - | - | - | - | - | - | - | ||||
| 2 | Blk | - | 5470 nM | - | - | - | - | - | - | - | ||||
| 3 | Lkb1 | - | >10000 nM | - | - | - | - | - | - | - | ||||
| 4 | Bmx | - | 1100 nM | - | - | - | - | - | - | - | ||||
| 5 | Btk | - | 5830 nM | - | - | - | - | - | - | - | ||||
| 6 | Itk | - | >30000 nM | - | - | - | - | - | - | - | ||||
| 7 | Insulin receptor | Purified protein kinase | >50000 nM | - | - | - | - | - | - | - | ||||
| 8 | PDGFr | Purified protein kinase | >50000 nM | - | - | - | - | - | - | - | ||||
| 9 | PKC | Purified protein kinase | >50000 nM | - | - | - | - | - | - | - | ||||
| 10 | Insulin receptor | Receptor phosphorylation in fibroblasts | >50000 nM | - | - | - | - | - | - | - | ||||
| 11 | PDGFr | Receptor phosphorylation in fibroblasts | >50000 nM | - | - | - | - | - | - | - | ||||
| 12 | cSrc-SM | - | 6400 nM | - | - | - | - | - | - | - | ||||
| 13 | cSrc-DM | - | >50000 nM | - | - | - | - | - | - | - | ||||