Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0002038 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Src | - | <100nM | - | - | - | - | - | - | - |
| 2 | CHK1 | - | >30000nM | - | - | - | - | - | - | - |
| 3 | FGF | - | >30000nM | - | - | - | - | - | - | - |
| 4 | IGF | - | >30000nM | - | - | - | - | - | - | - |
| 5 | JNK | - | >30000nM | - | - | - | - | - | - | - |
| 6 | KDR | - | >30000nM | - | - | - | - | - | - | - |
| 7 | PKA | - | >30000nM | - | - | - | - | - | - | - |
| 8 | PLK | - | >30000nM | - | - | - | - | - | - | - |
| 9 | ZAP70 | - | >30000nM | - | - | - | - | - | - | - |
| 10 | CSK | - | 10700nM | - | - | - | - | - | - | - |
| 11 | CDK2 | - | 17600nM | - | - | - | - | - | - | - |
| 12 | FAK | - | 19700nM | - | - | - | - | - | - | - |
| 13 | JAK3 | - | 20500nM | - | - | - | - | - | - | - |
| 14 | p38 | - | 27100nM | - | - | - | - | - | - | - |
| 15 | EphB2 | - | 50nM | - | - | - | - | - | - | - |
| 16 | EphB4 | - | 90 ± 50nM | - | - | - | - | - | - | - |
