Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0002994 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | CaMKII | - | >10000nM | - | - | - | - | - | - | - |
| 2 | ERK1 | - | >10000nM | - | - | - | - | - | - | - |
| 3 | MEK1 | - | >10000nM | - | - | - | - | - | - | - |
| 4 | p38 alpha | - | >10000nM | - | - | - | - | - | - | - |
| 5 | PKB alpha | - | >10000nM | - | - | - | - | - | - | - |
| 6 | ZAP | - | >10000nM | - | - | - | - | - | - | - |
| 7 | PKA | - | >20000nM | - | - | - | - | - | - | - |
| 8 | PKC | - | >20000nM | - | - | - | - | - | - | - |
| 9 | Src | - | >5000nM | - | - | - | - | - | - | - |
| 10 | cyclinD-Cdk1 | - | 120nM | - | - | - | - | - | - | - |
| 11 | Lck | - | 2300nM | - | - | - | - | - | - | - |
| 12 | Flt1 | - | 2800nM | - | - | - | - | - | - | - |
| 13 | cyclinD-Cdk4 | - | 42nM | - | - | - | - | - | - | - |
| 14 | PDGFR beta | - | 5000nM | - | - | - | - | - | - | - |
| 15 | FGFR1 | - | 6700nM | - | - | - | - | - | - | - |
| 16 | cyclinD-Cdk6 | - | 71nM | - | - | - | - | - | - | - |
| 17 | cyclinD-Cdk2 | - | 78nM | - | - | - | - | - | - | - |
