Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0004128 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | TIE2 | - | 11000nM | - | - | - | - | - | - | - |
| 2 | FLT3 | - | 20000nM | - | - | - | - | - | - | - |
| 3 | CDK2/CycA | - | 23000nM | - | - | - | - | - | - | - |
| 4 | CDK4/CycD1 | - | 27000nM | - | - | - | - | - | - | - |
| 5 | InsR | - | 27000nM | - | - | - | - | - | - | - |
| 6 | FAK | - | 28000nM | - | - | - | - | - | - | - |
| 7 | SAK | - | 28000nM | - | - | - | - | - | - | - |
| 8 | MET | - | 29000nM | - | - | - | - | - | - | - |
| 9 | Aurora A | - | 30000nM | - | - | - | - | - | - | - |
| 10 | BRAF-VE | - | 38000nM | - | - | - | - | - | - | - |
| 11 | PDGFR beta | - | 38000nM | - | - | - | - | - | - | - |
| 12 | Aurora B | - | 43000nM | - | - | - | - | - | - | - |
| 13 | SRC | - | 4400nM | - | - | - | - | - | - | - |
| 14 | VEGFR2 | - | 4400nM | - | - | - | - | - | - | - |
| 15 | VEGFR3 | - | 4800nM | - | - | - | - | - | - | - |
| 16 | IGF1R | - | 7700nM | - | - | - | - | - | - | - |
| 17 | COT | - | 9600nM | - | - | - | - | - | - | - |
