| General Property |
| Molceule ID (DB) | EGIN0003124 |
| Inhibitor Class | Quinoline |
| Molecule Name in Refrence Article | 14 compound |
| IUPAC Name | (1R,2R)-2-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}cyclopropane-1-carboxamide |
| Formula | C21H17Cl2FN2O2 |
| Mass | 419.276 |
| Exact Mass | 418.0651114 |
| Composition | C (60.16%), H (4.09%), Cl (16.91%), F (4.53%), N (6.68%), O (7.63%) |
| Atom Count | 45 |
| PI | 10.08 |
| Smiles | c12ncc(cc1cc(cc2)O[C@@H](c1c(ccc(c1Cl)F)Cl)C)[C@H]1[C@@H](C1)C(=O)N |
| InChI | 1S/C21H17Cl2FN2O2/c1-10(19-16(22)3-4-17(24)20(19)23)28-13-2-5-18-11(7-13)6-12(9-26-18)14-8-15(14)21(
25)27/h2-7,9-10,14-15H,8H2,1H3,(H2,25,27)/t10-,14+,15-/m1/s1 |
| InChIKey | QACCVOJRKKIYFM-WKPIXPDZSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 20093027 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | c-Met | EGFR | PDGFR | InsR | YES | Src | BRK | Abl | PKA | AKT1 | cdk1 | cdk2 | PKC-alpha | PKC-beta1 | PKC-beta2 | RON | AXL | LTK | FGFR2 | Flt3 | AuroraA | Fyn | IGF1R | lck | Kit | EphA2 | KDR | ALL |
| Pub Chem Link |
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| Drug Bank Link | - |
| ChemSpider Link | 24652526 |
| ChEMBL Link | CHEMBL602472 |
