| General Property |
| Molceule ID (DB) | EGIN0003447 |
| Inhibitor Class | Pyrimidine |
| Molecule Name in Refrence Article | 27 compound |
| IUPAC Name | (2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-c]pyrimidin-5-yl}amino)methyl]phenyl}prop-2-enoic acid |
| Formula | C25H24N6O5 |
| Mass | 488.4953 |
| Exact Mass | 488.1808179 |
| Composition | C (61.47%), H (4.95%), N (17.2%), O (16.38%) |
| Atom Count | 60 |
| PI | 4.8 |
| Smiles | c1(cc(cc(c1)OC)OC)Nc1nc(n2c(c1C(=O)N)ncc2)NCc1ccc(cc1)/C=C/C(=O)O |
| InChI | 1S/C25H24N6O5/c1-35-18-11-17(12-19(13-18)36-2)29-23-21(22(26)34)24-27-9-10-31(24)25(30-23)28-14-16-5
-3-15(4-6-16)7-8-20(32)33/h3-13,29H,14H2,1-2H3,(H2,26,34)(H,28,30)(H,32,33)/b8-7+ |
| InChIKey | LPKOEWTZGVUEJF-BQYQJAHWSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 19010686 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | ERK1 | Lck | p38a | PKC beta 2 | Src | Zap70 | Syk | JNK-1 | ALL |
| Pub Chem Link |
10005715
|
| Drug Bank Link | - |
| ChemSpider Link | 8181295 |
| ChEMBL Link | CHEMBL511829 |
