A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10033
Swiss-prot Accession numberP51918 (Sequence in FASTA format)
DescriptionProgonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)].
Source organismHaplochromis burtoni (Burton's mouthbrooder)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the GnRH family.
Tissue SpecificitySynthesized in preoptic neurons and is transported to the pituitary in the preoptic-hypophyseal axons
Post translational modificationN/A
FunctionStimulates the secretion of gonadotropins. May be responsible for the regulation of the hypothalamic-pituitary-gonadal axis
Protein Length94 Amino acids
Molecular weight10382
References1  PubMed abstract 7667296
2  PubMed abstract 9843638
3  PubMed abstract 7644702
Domain NameN/A
Hormone NameGonadoliberin-1
Mature Hormone SequenceQHWSYGLSPG
Position of mature hormone in Pre-Hormone protein10 Residues from position (23-32)
ReceptorQ5UKX6   Detail in HMRbase   
Q90YM3    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
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