A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number11390
Swiss-prot Accession numberP09240 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12866
References1  PubMed abstract 2011497
2  PubMed abstract 3862083
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVVPAEATDPVEQRAEEAPRRQLRAVLRPDREPRARLGALLARYIQQVRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorP56481   Detail in HMRbase   
O08786   Detail in HMRbase   
Q3TPL0   Detail in HMRbase   
Q3ZB46   Detail in HMRbase   
Q3ZB53   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene ID12424      
PDB IDN/A
Drugpediawiki
Comments