A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number11396
Swiss-prot Accession numberP09683 (Sequence in FASTA format)
DescriptionSecretin precursor.
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach
Protein Length121 Amino acids
Molecular weight13016
References1  PubMed abstract 11060443
2   Carlquist M., Joernvall H., Forssmann W.-G., Thulin L., Johansson C.,Mutt V.; "Human secretin is not identical to the porcine/bovine hormone."; IRCS Med. Sci. 13:217-218(1985).
Domain NameHormone_2  
Hormone NameSecretin
Mature Hormone SequenceHSDGTFTSELSRLREGARLQRLLQGLV
Position of mature hormone in Pre-Hormone protein27 Residues from position (28-54)
ReceptorQ8IV17   Detail in HMRbase   
P47872    Detail in HMRbase   
Gene ID6343      
PDB IDN/A
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