A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11510 |
| Swiss-prot Accession number | Q9DGC9 (Sequence in FASTA format) |
| Description | Progonadoliberin-2 precursor (Progonadoliberin II) (Chicken-type IIgonadotropin-releasing hormone) (cGnRH-II) [Contains: Gonadoliberin-2(Gonadoliberin II) (Luteinizing hormone-releasing hormone II) (LH-RHII) (Gonadotropin-releasing hormone II) (GnRH II) (Luliberin II);GnRH-associated peptide 2 (GnRH-associated peptide II)]. |
| Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | Expressed in the cell bodies of a cluster of neurons in the midbrain tegmentum |
| Post translational modification | N/A |
| Function | Stimulates the secretion of gonadotropins |
| Protein Length | 80 Amino acids |
| Molecular weight | 9311 |
| References | 1 PubMed abstract 11006121 2 PubMed abstract 12137956 |
| Domain Name | N/A |
| Hormone Name | Gonadoliberin-2 |
| Mature Hormone Sequence | QHWSHGWYPG |
| Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
| Receptor | Q76KC7 Detail in HMRbase Q76L92 Detail in HMRbase Q76L93 Detail in HMRbase Q90VY1 Detail in HMRbase Q90W00 Detail in HMRbase |
| Gene ID | 100049219 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |