A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1003
PubChem ID92810
Hormone name5-alpha-Dihydroprogesterone
DescriptionA biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR.
Synonyms3,20-Allopregnanedione 5-alpha-Dihydroprogesterone 3,20-Dioxo-5alpha-pregnane 5alpha-Pregnane-3,20-dione Allopregnane-3,20-dione 5beta-Pregnane-3,20-dione
Molecular weight316.48
Molecular formulaC21H32O2
IUPAC Name(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Canonical smilesCC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C
Isomeric smilesCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDC03681  
HMDB IDHMDB03759
Melting Point200(EXP)
Log P3.46(EST)
Water SolubilityN/A
DrugBank IDN/A
Drugpediawiki
ReceptorQ9GLW0   Detail in HMRbase   
P07812   Detail in HMRbase   
P06401   Detail in HMRbase   
P79373   Detail in HMRbase   
Q00175   Detail in HMRbase   
P06186   Detail in HMRbase   
Q8AYI2   Detail in HMRbase   
Q63449   Detail in HMRbase   
Q28590   Detail in HMRbase   
Q6Q6S5   Detail in HMRbase   
Q8NG42   Detail in HMRbase   
Q8NG43   Detail in HMRbase   
Q8NG44   Detail in HMRbase   
Q8TDS3   Detail in HMRbase   
Q8UVY3   Detail in HMRbase   
Comments!Link to Receptor is not Organism Specific
ReferencesPubchem,HMDB