A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 1082 |
| PubChem ID | 5920 |
| Hormone name | Triiodothyronine |
| Description | A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. |
| Synonyms | liothyronine Triiodothyronine Liothyronin L-Liothyronine triothyrone Lyothyronine Tresitope Tri-Thyrotope T3 liothyronine Triiodo-L-thyronine |
| Molecular weight | 650.97 |
| Molecular formula | C15H12I3NO4 |
| IUPAC Name | (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoicacid |
| Canonical smiles | C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O |
| Isomeric smiles | C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O
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| Structure | |
| PDB file | |
| SDF file | |
| MOL file | |
| PDB ID | 1BSX 1SN5 1XZX 2H6W 2H77 2H79 2PIV 2PIW |
| KEGG ID | C02465 |
| HMDB ID | HMDB00265 |
| Melting Point | 236.5(EXP) |
| Log P | 2.96(EST) |
| Water Solubility | 3.96(EXP) at 37C |
| DrugBank ID | DB00279 |
| Drugpedia | wiki |
| Receptor | P10827 Detail in HMRbase P10828 Detail in HMRbase P37243 Detail in HMRbase |
| Comments | |
| References | Pubchem |