A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10043
Swiss-prot Accession numberP82965 (Sequence in FASTA format)
DescriptionAntidiuretic factor A (ADFa) (ADF) (Antidiuretic hormone A) (ADHA).
Source organismTenebrio molitor (Yellow mealworm)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;Tenebrionidae; Tenebrio.
Subcellular locationSecreted
Developmental StageN/A
Similarity To T.molitor cuticular protein LPCP29 C-terminal region.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStrong inhibitor of fluid secretion by the Malpighian tubules. Uses cGMP as a second messenger and inhibits fluid production by decreasing cAMP concentration. Reduces isosmotic fluid secretion by inhibiting electroneutral and non-conductive transport pathways. Reverses the stimulatory effect of diuretic hormone I
Protein Length14 Amino acids
Molecular weight1543
References1  PubMed abstract 11756661
2  PubMed abstract 11893763
3  PubMed abstract 15235016
4  PubMed abstract 11756661
5  PubMed abstract 11893763
6  PubMed abstract 15235016
Domain NameN/A
Hormone NameAntidiuretic factor A
Mature Hormone SequenceVVNTPGHAVSYHVY
Position of mature hormone in Pre-Hormone protein14 Residues from position (1-14)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated