NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Ixocarpalactone A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
E2F1E2F transcription factor 11869Colon CancerSW-480----SW480 cells treated with IxoA showed cell cycle arrest in the G2/M phase, up-regulation of hyper-phosphorylated retinoblastoma, and down-regulation of E2F-1 and DP-1.17212786
TFDP1transcription factor Dp-17027Colon CancerSW-480----SW480 cells treated with Ixocarpalactone A showed cell cycle arrest in the G2/M phase, up-regulation of hyper-phosphorylated retinoblastoma, and down-regulation of E2F-1 and DP-1.17212786

 






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