Introduction
PEPlife is a manually curated database of experimentally validated therapeutic peptides and their halflives. In this database, peptides have been collected from both published articles as well as from patents.Each entry provides comprehensive information about a peptide that includes its sequence, chemical modifications incorporated, biological activity possessed, its half-life, the assay used to determine its half-life etc. In addition, tertiary structure of peptides have been predicted using PEPstrMOD and PEPstr.
Salient Features
Search Facility: User friendly module allows easy retrieval of relevant data according to user's query. User may perform search on any field of database usinf simple search, complex query processing using advanced search and atom level search using SIMILES search facility.
Browsing Facility: This module developed for class wise browsing of data. Information in PEPlife has been classified based on different criteria that includes peptide half-life, length, year of discovery.
Web based tools: Number of web-based tools have been integrated in PEPlife to facilitate users in performing similarity search, peptide mapping, sequence and structure alignment.