PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1092
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeActinobacillus pleuropneumoniae   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO chains of LPS of serotypes 4 and 7 were structurally similar, being composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone
BCSDB StructureN/A
Proposed functionsLPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
Antibodies2Mab5
Antibody type and classIgG2a
Assay SystemElisa inhibition assay
Cross-reactivityN/A
Proposed epitopesO-antigenic polysaccharide moeity inside the LPS. The epitope was proposed to include O-acetyl group of C6 position of glucose in the middle of repeating units
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation27-01-2010
References1384404


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