PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1196
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBrucella abortus 1119-3   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesKilled whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesB.ab.-5
Antibody type and classIgG1
Assay SystemWhole cell agglutination, immunodiffusion, immunoblotting and ELISA
Cross-reactivityThis Mab agglutinated Yersinia and Brucella abortus cells and had high ELISA titers, but which failed to precipitate the polysaccharide antigens
Proposed epitopesThe epitope was proposed to be Terminal nonreducing portions of the O-chain
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.
Curator IDAA + AS
Date of Curation04-03-2010
ReferencesPMC261544


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