PolysacDB ID | 2647 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A
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Proposed functions | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | N/A |
Conjugation Method | N/A |
Antibodies | IgG1 |
Antibody type and class | Mab S2 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross-reactivity | N/A |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 21-01-2012 |
References | PMC173659 |