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PolysacDB ID | 1374 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Coccidioides immitis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Coccidiodin along with spherulin |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab |
Antibody type and class | IgG1 |
Assay System | ELISA, immunoblotting and 2d-immunoelectrophoresis |
Cross-reactivity | This antibody was specific to Coccidiodes and did not cross-react with histoplasmin and blastocyanin |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This MAb would be useful as a probe for detecting circulating antigen in patients with coccidioidal disease and to assess the effect of passively transferred Mab on the pathogenesis of experimental murine coccidioidomycosis |
Curator ID | AA + AS |
Date of Curation | 02-07-2010 |
References | PMC313225 |
PolysacDB ID | 1634 |
Carbohydrate Name | Phenolic glycolipid antigen (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It consisting of terminal 3,6-di-O-methyl glucose linked β1-->4 to 2,3-di-O-methyl rhamnose, which in turn is linked α1-->2 to 3-O-methyl rhamnose |
BCSDB Structure | 114263 |
Proposed functions | It has been proposed to protect pathogenic mycobacteria such as Mycobacterium lepraemurium from the host bactericidal activities in phagocytic cells |
Antigenic Nature used to produce antibodies | Partially purified phenolic glycolipid from M. leprae |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab |
Antibody type and class | IgM |
Assay System | ELISA, TLC autoradiography and immunofluorescence |
Cross-reactivity | This Mab was specific to M. leprae glycolipid |
Proposed epitopes | Terminal 3,6-di-O-methyl glucose residues were proposed to be a part of the epitope |
IEDB Epitope | 76895 |
Proposed Utility | This Mab may provide more information on the structure of phenolic glycolipid of M. leprae and the localization of this antigen can be performed within infected lesions by immunofluorescence |
Curator ID | AA + AS |
Date of Curation | 26-09-2010 |
References | PMC263407 |
PolysacDB ID | 1778 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Mycoplasma mycoides (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | M. mycoides subsp. Mycoides integral membrane protein |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab |
Antibody type and class | IgM |
Assay System | ELISA, immunoblotting |
Cross-reactivity | N/A |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab had invivo growth inhibitory activity |
Curator ID | AA + AS |
Date of Curation | 29-10-2010 |
References | PMC170441 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |