PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1515
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeKlebsiella strains KD2   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO-1 side chain of the LPS is proposed to contain a disaccharide repeat unit consisting of [-α-D-Galp-(1->3)-β-D-Galf-] (1->4), where Gal is galactose
BCSDB StructureN/A
Proposed functionsThese major cell surface antigens play important roles in the ability of the bacterium to evade host cell defenses
Antigenic Nature used to produce antibodiesFormalinized whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 01-52.6
Antibody type and classN/A
Assay SystemELISA and immunoblotting
Cross-reactivityThis Mab reacted with high molecular weight LPS and did not recognize the LPS of P. haemolytica serotype 4
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antibody may help in the stuctural and functional elucidation of O1 side chain of Klebsiella LPS
Curator IDAA + AS
Date of Curation09-08-2010
ReferencesPMC259910


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