PolysacDB ID | 1732 |
Carbohydrate Name | Phenolic glycolipid-I (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Phenolic glycolipid-1 is a M. leprae-specific antigen that contains a unique trisaccharide, 3,6-di-O-methyl-β-D-glucopyranosyl-(1-->4)-2,3-di-O-methyl-α-L-rhamnopyranosyl-(1-->2)-3-O-methyl-α-L-rhamnopyranose
|
BCSDB Structure | N/A |
Proposed functions | It has been widely used for the serodiagnosis of leprosy and has been implicated in the pathogenesis of leprosy |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 1-25 |
Antibody type and class | N/A |
Assay System | Inhibitory ELISA |
Cross-reactivity | This Mab recognized the outer (nonreducing end) monosaccharide of the trisaccharide chain of PGL-I |
Proposed epitopes | N/A |
IEDB Epitope | 76905 |
Proposed Utility | This Mab promises to be an effective tool for the immunological study of PGL-I and the clinical assessment of leprosy |
Curator ID | AA + AS |
Date of Curation | 17-10-2010
|
References | 9465158 |