PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1732
Carbohydrate NamePhenolic glycolipid-I   (Drugpedia)
Carbohydrate ClassGlycolipid
MicrobeMycobacterium leprae   (NCBI Taxonomy)   (Drugpedia)
Basic StructurePhenolic glycolipid-1 is a M. leprae-specific antigen that contains a unique trisaccharide, 3,6-di-O-methyl-β-D-glucopyranosyl-(1-->4)-2,3-di-O-methyl-α-L-rhamnopyranosyl-(1-->2)-3-O-methyl-α-L-rhamnopyranose
BCSDB StructureN/A
Proposed functionsIt has been widely used for the serodiagnosis of leprosy and has been implicated in the pathogenesis of leprosy
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 1-25
Antibody type and classN/A
Assay SystemInhibitory ELISA
Cross-reactivityThis Mab recognized the outer (nonreducing end) monosaccharide of the trisaccharide chain of PGL-I
Proposed epitopesN/A
IEDB Epitope76905
Proposed UtilityThis Mab promises to be an effective tool for the immunological study of PGL-I and the clinical assessment of leprosy
Curator IDAA + AS
Date of Curation17-10-2010
References9465158


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