PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1266
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCandida albicans   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesFractions enriched for mitochondria and other membranous vesicles [membranous fraction] of Candida albicans
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 10G
Antibody type and classIgM
Assay SystemELISA, immunocollidal gold electron microscopy, indirect immunofuorescence assay, immunoelectrophoresis
Cross-reactivityYeast cells of 15 additional C. albicans strains and isolates of C. stellatoidka, C. tropicalis, C. intermedia and C. lusitaniae were also agglutinated by mAb 1OG. The antigen was not detected on other fungi, including Can&& krusei, C.utilis, Cryptococcus neoformans, Cr. albidus, Torulopsis glabrata, Rhodotorula spp. and Saccharomyces cerevisiae
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had a agglutinating activity against Candida albicans
Curator IDAA + AS
Date of Curation03-05-2010
References3280163


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