PolysacDB ID | 1971 |
Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Streptococcus pneumoniae serotype 6B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The capsular polysaccharide consists of the following residues : -2)-α-D-Galp-(1-->3)-α-D-Glcp-(1-->3)-α-L-Rhap-(1-->4)-D-Rib-ol-(5-P-
|
BCSDB Structure | 5205 |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Glycoconjugates |
Carrier Name | Tetanus toxoid |
Conjugation Method | The oligosaccharide was derivatized with adipic acid dihydrazide and coupled to tetanus toxoid |
Antibodies | Mab 10H8 |
Antibody type and class | IgG1 |
Assay System | Enzyme Inhibition Assay, colony blotting, Opsonophagocytosis assay |
Cross-reactivity | This Mab reacted with polysaccharides from 11A, 19F and 23F strain but did not recognize type 6A polysaccharide |
Proposed epitopes | Disaccharide rhamnose-(1-->4)-ribitol phosphate residues seemed to be the part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 08-12-2010
|
References | PMC95896 |