PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1317
Carbohydrate NamePhosphomannan protein complex   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCandida albicans NIH B-792   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesHeat-killed yeast-form cells of Candida albicans NIH B-792 strain
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 10b12
Antibody type and classIgM
Assay SystemN/A
Cross-reactivityThis antibody cross-reacted with NIH A-207 (serotype A) and J-1012 [serotype A] and C. tropicalis IFO 0630
Proposed epitopesThe epitope was proposed to contain β-1,2-linked oligomannosyl residues
IEDB EpitopeN/A
Proposed UtilityAntibodies to β- 1,2-linked oligomannosyl residues can be used as the serodiagnostic agent for detecting the C. albicans antigen(s) in sera and tissues of mammals with candidiasis.
Curator IDAA + AS
Date of Curation08-06-2010
References3280163


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036