PolysacDB ID | 1532 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Klebsiella pneumoniae O1:K2 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | It has been shown to be an important virulence factor and potent antigen for the induction of immunoprotection |
Antigenic Nature used to produce antibodies | LPS-associated proteins plus LPS |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 12B6 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This Mab cross-reacted with K. pneumoniae R:K18, a rough strain. This Mab did not cross-react with LPS from Klebsiella strains of the 02, 03, and 04 serotypes nor LPS from E. coli 0111:B4 |
Proposed epitopes | This Mab recognized the LPS core |
IEDB Epitope | N/A |
Proposed Utility | This Mab showed invivo protection in mice against LPS induced homologous shock |
Curator ID | AA + AS |
Date of Curation | 27-08-2010
|
References | PMC313574 |