PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1057
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEscherichia coli O26:H11   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-polysaccharide is composed of trisaccharide repeating units having the following structure. -->3)-α-L-Rhap-(1-->4)-α-L-FucpNAc-(1-->3)-β-D-GlcpNAc-(1-->
BCSDB Structure20653
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 12F5
Antibody type and classIgM
Assay SystemELISA, immunoblotting
Cross-reactivityThis antibody cross-reacted with E. coli O4:NM strain and other E. coli O-negative:NM field isolates
Proposed epitopesO-antigen was proposed to be the epitope
IEDB EpitopeN/A
Proposed UtilityThese MAb have a potential use as immunodiagnostic reagents whether used alone or in combination with other phenotypic or genotypic markers
Curator IDAA + AS
Date of Curation17-01-2010
ReferencesPMC92269


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