PolysacDB ID | 2555 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Vibrio cholerae serogroup O139 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
Antigenic Nature used to produce antibodies | Whole cell lysates |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 12F5-G2 |
Antibody type and class | IgG2b |
Assay System | Dot-blot ELISA, immunoblotting, ELISA |
Cross-reactivity | This Mab was specific to Vibrio cholerae serogroup O139 and did not cross-react with 137 strains of other enteric microorganisms |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used as a detection reagent in the antigen detection assay for diagnosis of cholera caused by V. cholerae O139 |
Curator ID | AA + AS |
Date of Curation | 25-06-2011
|
References | 9817879 |