PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1786
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeMyxococcus xanthus   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-chain was built up of disaccharide repeating units having the following structure: -->6)-α-D-Glcp-(1-->4)-α-D-GalpNAc6oMe*-(1--> with partially methylated GalNAc residue.
BCSDB Structure21880
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 1412
Antibody type and classIgM
Assay SystemELISA, immunoblotting
Cross-reactivityThis Mab was specific to M. xanthus and did not bind to LPS of any other gram negative bacteria
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis MAb may be a useful probe for detecting specific alterations in the LPS structure which may occur during the development of M. xanthus. This Mab has been used to isolate many LPS biosynthesis mutants
Curator IDAA + AS
Date of Curation31-10-2010
ReferencesPMC209853


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