PolysacDB ID | 1240 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Brucella melitensis Rev1 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | O-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Whole B. melitensis Cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 15B1G10 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This Mab was specific to A and M strains of Brucella and did not cross-react with S-LPSs of S. urbana, Vibrio cholerae and E. coli O:157 but bound better to M-dominant S-LPS than to A-dominant S-LPS |
Proposed epitopes | This Mab was specific to the C epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab helped in the epitope strucure elucidation |
Curator ID | AA + AS |
Date of Curation | 03-04-2010
|
References | PMC175246 |