| PolysacDB ID | 2043 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Pseudomonas aeruginosa (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core region of LPS is divided into the outer core and inner core. The inner core region consists of 2-keto-3-deoxyoctonic acid (KDO), heptose, phosphate, and probably ethanolamine. The outer core region commonly contains D-glucose, L-rhamnose, D-galactosamine, and L-alanine. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
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| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Formalin killed whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 18-19 |
| Antibody type and class | IgG3 |
| Assay System | ELISA, immunoblotting, ouchterlony immunodiffusion |
| Cross-reactivity | "This Mab cross-reacted with Serotypes O2, O5 and O16" |
| Proposed epitopes | In addition to the O-antigen part, this Mab also binds to the core region |
| IEDB Epitope | 76837 |
| Proposed Utility | This Mab helps us shed some light on the nature of O-specific and common epitopes in the LPS of P. aeruginosa |
| Curator ID | AA + AS |
| Date of Curation | 26-12-2010
|
| References | PMC205836 |