PolysacDB ID | 1877 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Neisseria gonorrhoeae (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Gonococcal lipopolysaccharide (LPS) is a complex of at least three major antigenic determinants. The ceramide part consists of the following residues : β-D-GalpNAc-(1-->3)-β-D-Galp-(1-->4)-β-D-Glcp-(1-?)-CER-(?--/Ceramide/. The core oligosaccharide part consists of the following residues : α-D-GlcpNAc-(1-->2)-L-gro [branched to β-D-Galp-(1-->4)-β-D-Glcp-(1-->4)] -α-D-manHepp-(1-->3)-L-gro-α-D-manHepp-(1-->5)-Kdo. The other part consists of the following residues : β-D-GalpNAc-(1-->3)-β-D-Galp-(1-->4)-β-D-GlcpNAc-(1-->3)-β-D-Galp-(1-->4)-β-D-Glcp-(1-->4)-L-gro [branched to α-D-GlcpNAc-(1-->2)-L-gro-α-D-manHepp-(1-->3)] -α-D-manHepp-(1-->5)-Kdo
|
BCSDB Structure | 134700 |
Proposed functions | It is an important virulence factor |
Antigenic Nature used to produce antibodies | Gonococcal outer membranes |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 2C7 |
Antibody type and class | IgG3 |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This Mab was broadly cross-reactive among Neisseria gonorrhoeae strains except among WR213, F62, 8038-5, DAV, 6611-33, GC33 and WR302 |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 20-11-2010
|
References | PMC260117 |