| PolysacDB ID | 1741 |
| Carbohydrate Name | Phenolic glycolipid-I (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Phenolic glycolipid-1 is a M. leprae-specific antigen that contains a unique trisaccharide, 3,6-di-O-methyl-β-D-glucopyranosyl-(1-->4)-2,3-di-O-methyl-α-L-rhamnopyranosyl-(1-->2)-3-O-methyl-α-L-rhamnopyranose
|
| BCSDB Structure | N/A |
| Proposed functions | It has been widely used for the serodiagnosis of leprosy and has been implicated in the pathogenesis of leprosy |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 2G3-A8 |
| Antibody type and class | N/A |
| Assay System | Inhibitory ELISA |
| Cross-reactivity | MAb 2G3-A8 recognized the inner monosaccharide, phenol group and the structure around the branching point on the carrier protein |
| Proposed epitopes | N/A |
| IEDB Epitope | 76905 |
| Proposed Utility | This Mab promises to be an effective tool for the immunological study of PGL-I and the clinical assessment of leprosy |
| Curator ID | AA + AS |
| Date of Curation | 20-10-2010
|
| References | 9465158 |