PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1858
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis group C strain C11   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consists of a homopolymer of α(2-->9)-linked sialic acid residues
BCSDB StructureN/A
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 3079.6
Antibody type and classIgG3
Assay SystemFluorescence ELISA, Ouchterlony precipitation, Bacterial agglutination assay, Bactericidal assay
Cross-reactivityThis Mab reacted with natural O-acetyl-negative variant (OAc-, strain MC19) polysaccharide and did not react with K1 polysaccharide
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had bactericidal activity
Curator IDAA + AS
Date of Curation16-11-2010
References3143763


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